Dr. Richard S. Legro - Convidado internacional da Reciclagem S.O.P. 2011

Richard S. Legro, M.D., FACOG

Penn State Hershey Obstetrics and Gynecology

Fellowship, Reproductive Endocrinology, University of Southern California - Berkley/Keck School of Medicine (1993) Residency, OB/Gyn, Magee-Women's Hospital, University of Pittsburgh (1991) M.D., Mount Sinai School of Med. of the City University of NY (1987)

Últimos trabalhos publicados pelo Dr. Legro e colaboradores.  

1

Estimating rates of multiple gestation pregnancies: Sample size calculation from the assessment of multiple intrauterine gestations from ovarian stimulation (AMIGOS) trial.

Diamond MP, Mitwally M, Casper R, Ager J, Legro RS, Brzyski R, Casson P, Eisenberg E, Zhang H; for the NICHD Cooperative Reproductive Medicine Network.

Contemp Clin Trials. 2011 Jul 20.

2.

Racial influence on the polycystic ovary syndrome phenotype: a black and white case-control study.

Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS.

Fertil Steril. 2011 Jul;96(1):224-229.e2.

3.

Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study.

Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Lee PA, Williams NI, Coney P, Legro RS.

Fertil Steril. 2011 Jun 30;95(8):2595-2598.e6.

4.

Increasing burden of institutional review in multicenter clinical trials of infertility: the Reproductive Medicine Network experience with the Pregnancy in Polycystic Ovary Syndrome (PPCOS) I and II studies.

Schlaff WD, Zhang H, Diamond MP, Coutifaris C, Casson PR, Brzyski RG, Christman GM, Barnhart KT, Trussell JC, Krawetz SA, Snyder PJ, Ohl D, Santoro N, Eisenberg E, Huang H, Legro RS; Reproductive Medicine Network.

Fertil Steril. 2011 Jul;96(1):15-8.

5.

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome.

Jones MR, Chua A, Chen YD, Li X, Krauss RM, Rotter JI, Legro RS, Azziz R, Goodarzi MO.

PLoS One. 2011;6(5):e20120..

6.

Metformin as adjuvant therapy to IVF in women with PCOS: when is intention-to-treat unintentional?

Legro RS.

Hum Reprod. 2011 Aug;26(8):2043-4. Epub 2011 May 23.

7.

Evidence for increased cardiovascular events in the fathers but not mothers of women with polycystic ovary syndrome.

Taylor MC, Reema Kar A, Kunselman AR, Stetter CM, Dunaif A, Legro RS.

Hum Reprod. 2011 Aug;26(8):2226-31.

8.

The physiological basis of complementary and alternative medicines for polycystic ovary syndrome.

Raja-Khan N, Stener-Victorin E, Wu X, Legro RS.

Am J Physiol Endocrinol Metab. 2011 Jul;301(1):E1-E10.

9.

Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome.

Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF 3rd.

Fertil Steril. 2011 Jun 30;95(8):2538-2541.e6.

10.

Incomplete and inconsistent reporting of maternal and fetal outcomes in infertility treatment trials.

Dapuzzo L, Seitz FE, Dodson WC, Stetter C, Kunselman AR, Legro RS.

Fertil Steril. 2011 Jun 30;95(8):2527-30.

11.

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.

Ewens KG, Jones MR, Ankener W, Stewart DR, Urbanek M, Dunaif A, Legro RS, Chua A, Azziz R, Spielman RS, Goodarzi MO, Strauss JF 3rd.

PLoS One. 2011 Jan 20;6(1):e16390.

12.

Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome.

Wickham EP 3rd, Ewens KG, Legro RS, Dunaif A, Nestler JE, Strauss JF 3rd.

J Clin Endocrinol Metab. 2011 Apr;96(4):E719-27.

13.

The effects of metformin with lifestyle therapy in polycystic ovary syndrome: a randomized double-blind study.

Ladson G, Dodson WC, Sweet SD, Archibong AE, Kunselman AR, Demers LM, Williams NI, Coney P, Legro RS.

Fertil Steril. 2011 Mar 1;95(3):1059-66.e1-7.

14.

PCOS Forum: research in polycystic ovary syndrome today and tomorrow.

Pasquali R, Stener-Victorin E, Yildiz BO, Duleba AJ, Hoeger K, Mason H, Homburg R, Hickey T, Franks S, Tapanainen JS, Balen A, Abbott DH, Diamanti-Kandarakis E, Legro RS.

Clin Endocrinol (Oxf). 2011 Apr;74(4):424-33. doi: 10.1111/j.1365-2265.2010.03956.x.

15.

Effects of atorvastatin on vascular function, inflammation, and androgens in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial.

Raja-Khan N, Kunselman AR, Hogeman CS, Stetter CM, Demers LM, Legro RS.

Fertil Steril. 2011 Apr;95(5):1849-52.

16.

Metformin during pregnancy in polycystic ovary syndrome: another vitamin bites the dust.

Legro RS. J Clin Endocrinol Metab. 2010 Dec;95(12):5199-202..

17.

Brachial artery conductance during reactive hyperemia is increased in women with polycystic ovary syndrome.

Raja-Khan N, Shuja SA, Kunselman AR, Hogeman CS, Demers LM, Gnatuk CL, Legro RS.

Eur J Obstet Gynecol Reprod Biol. 2011 Mar;155(1):49-53.

18.

Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism.

Legro RS, Schlaff WD, Diamond MP, Coutifaris C, Casson PR, Brzyski RG, Christman GM, Trussell JC, Krawetz SA, Snyder PJ, Ohl D, Carson SA, Steinkampf MP, Carr BR, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Myers ER, Santoro N, Eisenberg E, Zhang M, Zhang H; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2010 Dec;95(12):5305-13.

19.

Decision trees for identifying predictors of treatment effectiveness in clinical trials and its application to ovulation in a study of women with polycystic ovary syndrome.

Zhang H, Legro RS, Zhang J, Zhang L, Chen X, Huang H, Casson PR, Schlaff WD, Diamond MP, Krawetz SA, Coutifaris C, Brzyski RG, Christman GM, Santoro N, Eisenberg E; Reproductive Medicine Network.

Hum Reprod. 2010 Oct;25(10):2612-21.

20.

A variant in the fibrillin-3 gene is associated with TGF-β and inhibin B levels in women with polycystic ovary syndrome.

Raja-Khan N, Kunselman AR, Demers LM, Ewens KG, Spielman RS, Legro RS.

Fertil Steril. 2010 Dec;94(7):2916-9.

21.

Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years.

Williams NI, Reed JL, Leidy HJ, Legro RS, De Souza MJ.

Hum Reprod. 2010 Sep;25(9):2328-39. ns

22.

Effect of air quality on assisted human reproduction.

Legro RS, Sauer MV, Mottla GL, Richter KS, Li X, Dodson WC, Liao D.

Hum Reprod. 2010 May;25(5):1317-24.

23.

Family-based analysis of candidate genes for polycystic ovary syndrome.

Ewens KG, Stewart DR, Ankener W, Urbanek M, McAllister JM, Chen C, Baig KM, Parker SC, Margulies EH, Legro RS, Dunaif A, Strauss JF 3rd, Spielman RS.

J Clin Endocrinol Metab. 2010 May;95(5):2306-15.

24.

Associations of birthweight and gestational age with reproductive and metabolic phenotypes in women with polycystic ovarian syndrome and their first-degree relatives.

Legro RS, Roller RL, Dodson WC, Stetter CM, Kunselman AR, Dunaif A.

J Clin Endocrinol Metab. 2010 Feb;95(2):789-99.

25.

High prevalence of metabolic syndrome in first-degree male relatives of women with polycystic ovary syndrome is related to high rates of obesity.

Coviello AD, Sam S, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2009 Nov;94(11):4361-6.

26.

Peripubertal estrogen levels and physical activity affect femur geometry in young adult women.

Devlin MJ, Stetter CM, Lin HM, Beck TJ, Legro RS, Petit MA, Lieberman DE, Lloyd T.

Osteoporos Int. 2010 Apr;21(4):609-17.

27.

Insulin resistance in women's health: why it matters and how to identify it.

Legro RS.

Curr Opin Obstet Gynecol. 2009 Aug;21(4):301-5. Review.

28.

Body mass index and intercourse compliance.

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC; National Institute of Child Health and Human Development-Reproductive Medicine Network.

Fertil Steril. 2010 Sep;94(4):1447-50.

29.

Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial.

Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice LC; National Institute of Child Health and Human Development-Reproductive Medicine Network.

Fertil Steril. 2010 Sep;94(4):1444-6.

30.

Predictors of pregnancy in women with polycystic ovary syndrome.

Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER, Coutifaris C; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2009 Sep;94(9):3458-66.

31.

PDE8A genetic variation, polycystic ovary syndrome and androgen levels in women.

Chen C, Wickenheisser J, Ewens KG, Ankener W, Legro RS, Dunaif A, McAllister JM, Spielman RS, Strauss JF 3rd.

Mol Hum Reprod. 2009 Aug;15(8):459-69.

32.

The role of genetic variation in the lamin a/c gene in the etiology of polycystic ovary syndrome.

Urbanek M, Nampiaparampil G, D'Souza J, Sefton E, Ackerman C, Legro RS, Dunaif A.

J Clin Endocrinol Metab. 2009 Jul;94(7):2665-9.

33.

Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2.

Biyasheva A, Legro RS, Dunaif A, Urbanek M.

J Clin Endocrinol Metab. 2009 Jul;94(7):2617-25.  

34.

Heirarchical clustering and beyond in PCOS endometrium: brave new world.

Legro RS, McAllister JM.

J Clin Endocrinol Metab. 2009 Apr;94(4):1084-5.

35.

Epinephrine is associated with both erectile dysfunction and lower urinary tract symptoms.

Trussell JC, Kunselman AR, Legro RS.

Fertil Steril. 2010 Feb;93(3):837-42.

36.

Impact of metformin, oral contraceptives, and lifestyle modification on polycystic ovary syndrome in obese adolescent women: do we need a new drug?

Legro RS. J Clin Endocrinol Metab. 2008 Nov;93(11):4218-20.

37.

The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale HF, Futterweit W, Janssen OE, Legro RS, Norman RJ, Taylor AE, Witchel SF; Task Force on the Phenotype of the Polycystic Ovary Syndrome of The Androgen Excess and PCOS Society.

Fertil Steril. 2009 Feb;91(2):456-88.. Review.

38.

Individualizing infertility therapy with pharmacogenomics: vanity or vanguard?

Legro RS. Pharmacogenomics. 2008 Sep;9(9):1179-81.

39.

Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome.

Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC; Reproductive Medicine Network.

J Clin Endocrinol Metab. 2008 Aug;93(8):3124-7.

40.

Metabolic phenotype in the brothers of women with polycystic ovary syndrome.

Sam S, Coviello AD, Sung YA, Legro RS, Dunaif A.

Diabetes Care. 2008 Jun;31(6):1237-41.